Original Articles Vol. 3 No. 02 (2026): Bioscience Insights Published 2026-08-31

CRISPR-CAS13A MEDIATED KNOCKDOWN OF ACRB MRNA EXPRESSION RESTORES CIPROFLOXACIN SUSCEPTIBILITY IN MULTIDRUG-RESISTANT KLEBSIELLA PNEUMONIAE

Authors

  • Raiha Ausaf Khan Kauser Abdulla Malik School of Life Sciences, Forman Christian College University Lahore Pakistan Author
  • Zeeshan Ahmad Kauser Abdulla Malik School of Life Sciences, Forman Christian College University Lahore Pakistan Author
  • Laiba Wadood Department of Pharmacy, The University of Lahore Pakistan Author
  • Asim Patrick Department of Microbiology, Government College University Hyderabad, Sindh, Pakistan Pakistan Author
  • Qandeel Abbas Soomro Department of Pathology, Indus Medical College, The University of Modern Science, Tando Muhammad Khan Sindh, Pakistan Pakistan Author
  • Amna Noor Department of Pathology, Rawalpindi Medical University, Pakistan Author
  • Raza Ullah Khan Centre for Omic Sciences, Islamia College Peshawar, KPK, Pakistan Pakistan Author
  • Sheeza Riaz Department of Pharmacy, M. Islam college of pharmacy, Gujranwala Punjab Pakistan Author
  • Urooj Fatima Department of Pharmacy, University of Lahore, Punjab Pakistan Pakistan Author
  • Maaz Ahmad MBBS, NUMS (Army Medical College) Pakistan Author
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Abstract

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Keywords

  • CRISPR-Cas13a, acrB Efflux Pump, Klebsiella pneumoniae, Ciprofloxacin Resistance, Multidrug Resistance, Transcriptional Knockdown, Antimicrobial Resistance.

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